Tuesday, 24 April 2018

Medical experts offer fresh hope for surviving migraine

04 December 2017 | News

By blocking CGRP, doctors hope to break the cycle of increasing inflammation and increased pain sensitivity that contributes to migraine headaches.

Image credit- everytimeinfo.com

Image credit- everytimeinfo.com

A group of researchers in the US has identified a medication that can prevent the severe headaches before they start.

The drug called Fremanezumab, developed by Teva Pharmaceuticals, is a biological agent that binds to and blocks the action of a migraine-associated protein called calcitonin gene-related peptide (CGRP). Mounting evidence of its importance in migraines has made this peptide a focal point of research and drug development.

The peptide is released at high levels during migraine in response to inflammation, and triggers a cascade effect that stimulates more of its release. This results in increasing sensitivity of the brain to pain.

By blocking this peptide, doctors hope to break the cycle of increasing inflammation and increased pain sensitivity that contributes to migraine headaches.

Another study was also conducted tested the effectiveness of the drug erenumab, co-developed by Novartis and Amgen, in people suffering from migraine.

Both drugs have been submitted for approval by the Food and Drug Administration, and their manufacturers hope to introduce them to the market in 2018.

Comments

× Your session has been expired. Please click here to Sign-in or Sign-up
   New User? Create Account





Survey Box

Can access to vaccines reduce the threat of antibiotic resistance?

× Please select an option to participate in the poll.
Processing...   View poll results   More polls

× You have successfully cast your vote.
{{ optionDetail.option }}{{ optionDetail.percentage }}%
{{ optionDetail.percentage }}% Complete
More polls