Sunday, 09 August 2020

NCPOR, GU synthesise gold nanoparticles for therapeutic use

07 July 2020 | News

Can be used as a composite therapeutic agent clinical trials, especially in anti-cancer, anti-viral, anti-diabetic, and cholesterol-lowering drugs

Image credit- shutterstock.com

Image credit- shutterstock.com

The National Centre for Polar and Ocean Research (NCPOR) and the Goa University (GU) have successfully synthesized gold nanoparticles (GNPs) using psychrotolerant Antarctic bacteria  through a non-toxic, low-cost, and eco-friendly way.

Through a study, NCPOR and GU have established that 20-30-nm-sized spherical-shaped GNPs could be synthesized in a controlled environment.

These GNPs can be used as a composite therapeutic agent clinical trials, especially in anti-cancer, anti-viral, anti-diabetic, and cholesterol-lowering drugs.

The NCPOR-GU study revealed genotoxic effect of GNPs on a sulphate reducing bacteria (SRB). The GNPs displayed enough anti-bacterial properties by inhibiting the growth of SRB and its sulphide production by damaging the genetic information of the DNA of the bacterial cell. Genotoxicity describes the property of a chemical agent that is capable of damaging the genetic information of DNA and thus causing mutation of the cell, which can lead to cancer.

Nanoparticles (NPs) have wide variety of potential applications in the fields of biomedical, optical and electronics research. Metallic NPs have been efficiently exploited for biomedical applications and among them GNPs are found to be effective in biomedical research.

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