• Mumbai
  • 12 June 2013
  • Views
  • By Dr.Samir Brahmachari, chief mentor, Open Source Drug Discovery and director general, Council for Scientific and Industrial Research (CSIR)

'We must break bottlenecks and forge ahead', says Dr.Brahmachari

The chief mentor for the ambitious Open Source Drug Discovery program and director general,CSIR,Dr.Samir Brahmachari speaks about how even though the education sector in biotech has been a disappointment, India can be a leader in the future


Dr.Samir Brahmachari, chief mentor, Open Source Drug Discovery and director general, Council for Scientific and Industrial Research (CSIR)

We have a great future ahead if we start putting more efforts on data intensive research in drug discovery.As I go down the memory lane of the decade, I can remember the striking development that took place in 2003. It was the launch of a world-class magazine, BioSpectrum. There is no other field in India that has been so well covered and chronicled both in terms of extensive coverage and statistical development as the way CyberMedia does with this industry.

In 2002, biotechnology was just in its nascent stage and was considered to be a small industry. But the success story of vaccine sector and the emergence of companies such as Bharat Biotech and Shantha Biotech changed the course and direction. Also, the success of Biocon has been a major milestone that brought recognition and growth along with stability to the industry. The emergence of bioinformatics as a discipline, genomics as a research area and contract research as an opportunity are the remarkable feats of this industry. All these areas have evolved over the decade.

Although, presently, the biotech industry is close to $5 billion, yet, it cannot be compared to large industries such as petrochemical, automobile and information technology, but the impact is quite significant. The growth of scientific institutions have given fillip to the pharma, agriculture and other areas. In fact, our new national biology laboratories are just 25 years old. It is in the late 80s that the best laboratories came up in life sciences. Be it CSIR, DBT or DAE institutes, all have made significant contributions not only in therapeutics but in generics as well. I think they have paved the way for such an exciting journey. My own experiences at CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh have been phenomenal. The thrombolytic molecules developed at the institute from being niche to being wide spread and affordable, has been remarkable. As we speak, a novel clot buster in form of clot specific streptokinase is about to undergo the final stage clinical trials. So, we have crossed a major milestone at CSIR.

The affordability in healthcare has basically come from the success in the chemical industry and that has been now extended to the vaccines. The challenge remains that, how will we get new molecules developed and for that various steps have to be taken including the leveraging of existing knowledge treasure on the available drugs.

The disappointment however remains with the education sector where we have large number of students with sky-high expectations and yet failing to get into right spaces. The absorption capacity has not met the expectations of those who were looking for job opportunities. The industrial consumption of manpower has not grown commensurate to the development of human resources. Specific verticals such as bioinformatics are yet to be tapped fully. The potential growth in informatics has not been exploited to the level that should have been by the large industries. Except Tata Consultancy Services in IT industry, no other company has utilized its full potential.


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