Epiviz: A tool to analyze human genomic data

Researchers at the University of Maryland, have developed a novel web-based tool to better analyze human genomic data

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Epiviz links data across different visualizations giving users visual insights of the spatial relationships of multiple datasets

Researchers at the University of Maryland (UMD) report the development of a new, web-based tool that enables researchers to quickly and easily visualize and compare large amounts of genomic information resulting from high-throughout sequencing experiments. The free tool, called Epiviz, was described in a paper (Epiviz: interactive visual analytics for functional genomics data) published online in Nature Methods.

"Epiviz seamlessly integrates with the open-source Bioconductor analysis software widely used by genomic scientists, through its Epivizr Bioconductor package," said Mr Héctor Corrada-Bravo, PhD assistant professor in computer science at UMD.

"Epiviz, a web-based genome browser, and the Epivizr Bioconductor package allows interactive, extensible, and reproducible visualization within a state-of-the-art data-analysis platform," explained the investigators.

"Prior tools limited visualization to presentation and dissemination, rather than a hybrid tool integrating interactive visualization with algorithmic analysis," explained Mr Corrada-Bravo.

It supports many popular next-generation sequencing techniques, such as ChIP-seq, which is used to analyze protein interactions with DNA; RNA-seq, which reveals a comprehensive snapshot of the abundance of RNAs in cells; and DNA methylation analyses.

 

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